Harrisburg, PA – Injuries Reported in Multi-Vehicle Crash on I-81 NB/Exit 66

Harrisburg, PA (November 3, 2025) – Several people were injured following a multi-vehicle collision on Interstate 81 northbound near Exit 66, close to Downtown Harrisburg and Front Street, on Monday, November 3. According to the Pennsylvania State Police, the crash occurred during the morning rush hour, involving multiple vehicles that collided in the middle lanes of the highway.

The impact caused significant traffic delays as emergency crews responded to the scene to assist the victims. First responders provided on-site medical aid to the injured motorists, and at least one person was transported to a nearby hospital for further evaluation. Several vehicles sustained heavy damage, and tow trucks were called to remove the wreckage. Authorities temporarily closed affected lanes while investigating the cause of the crash.

Traffic has since been restored, but officials continue to examine the circumstances that led to the collision.

We extend our best wishes for a full and swift recovery to those hurt in this incident.

If you or someone you love has been injured in a crash on I-81, don’t wait to seek help. Contact our experienced car accident lawyers today to discuss your legal options and get the justice you deserve.